Hey, brother! I fish in Maysville alot through the spring and summer. I always go down by City Park or down by where the barges sometimes dock. I don't know what it is called but it is on the right of the bridge on the Maysville side.
You will have luck fishing the manmade structure: barges and docks. Also try to get on the down stream side of any warm water discharges. I am not too familar with the KY side, but just across the river on the ohio side you could fish the area around 5-mile creek, just as it comes into the river and that hole should hold some big fish.